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KMID : 1144120120020020124
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Biomedical Engineering Letters
2012 Volume.2 No. 2 p.124 ~ p.128
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Influence of orientation and area of the extended cortical current source on the magnetoencephalography (MEG) inverse problem
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Choi Jong-Ho
Luan Feng
Kim Min-Hyuk
Jung Hyun-Kyo
Im Chang-Hwan
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Abstract
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Purpose: In this paper, we investigated the influence of orientation and activation area of extended cortical current sources upon the solutions of magnetoencephalography (MEG) inverse problems.
Methods: Extensive simulation studies were performed with artificial MEG datasets generated using a realistic head geometry model.
Results: Our simulation studies demonstrated that as the source activation area was extended beyond a threshold level, the radial component of cortical sources was weakened and thus the accuracy of MEG inverse problem was enhanced.
Conclusions: These are important findings suggesting that one may not need to be concerned too much about the insensitivity of MEG to radial sources in many practical MEG measurements.
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KEYWORD
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Distributed source model, Magnetoencephalography (MEG), Neuroelectromagnetic inverse problem, Source imaging
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